What You Should Know:
– Circulate Health, a pioneer in Therapeutic Plasma Exchange (TPE) technologies, has secured a seven-figure strategic investment from Scrum Ventures.
– The funding will accelerate the company’s growth as it works to position TPE as a scalable, patient-centered solution for longevity care. Circulate’s platform leverages TPE to remove microplastics, environmental toxins, and inflammatory markers from the bloodstream, addressing the growing consumer demand for proactive health and anti-aging solutions.
The Convergence of Longevity and Environmental Health
The conversation around modern health is rapidly shifting from reactive disease management to proactive, science-backed longevity care. At the center of this transformation sits Circulate Health, a leader in precision Therapeutic Plasma Exchange (TPE) technologies and microplastics technologies.
Circulate Health today announced a strategic investment from Scrum Ventures, a global early-stage venture capital firm known for its strong focus on human performance and next-generation health technologies. This partnership, signaled by a seven-figure investment, will fuel Circulate’s ongoing growth.
TPE: A New Frontier in Blood Maintenance
Therapeutic Plasma Exchange (TPE), the core of Circulate Health’s platform, is a specialized medical procedure in which plasma, the liquid portion of your blood, is removed and replaced with a substitute solution, typically made of albumin and saline. This process filters out harmful substances such as toxins, pro-inflammatory proteins, and heavy metals.
Circulate Health’s platform leverages advanced TPE technology designed to remove circulating microplastics, environmental toxins, inflammatory markers, and other microscopic pollutants. Early research suggests that the accumulation of these particles may contribute to systemic inflammation, oxidative stress, and potential long-term health challenges. TPE is hypothesized to “reset” inflammatory signaling networks and remove age-related proteins that accumulate in chronic inflammatory states.
- TPE is sometimes called an “oil change” for the bloodstream.
- The procedure can clear toxic substances such as mold, heavy metals, viruses, and microplastics.
- It has been shown to reduce neurotoxic proteins like beta-amyloid, which may help slow cognitive decline.
- The process can remove autoantibodies and help manage autoimmune conditions.
Brad Younggren, Circulate’s CEO and Co-Founder, said consumers are “recognizing the benefits of TPE”. The partnership with Scrum Ventures signals the convergence of two rapidly growing fields and follows a $12 million seed funding round led by Khosla Ventures earlier in 2025.
